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From the Department of Ophthalmology, Fundacion Oftalmologica de Santander (Ossma, Galvis), Bucaramanga, Colombia; Visiogen Inc.(Vargas), Irvine, California, and the Department of Ophthalmology, University of California San Francisco (Trager, Vagefi, Mc Leod), San Francisco, California, USAA prospective noncomparative case series with retrospective control comprised 21 patients (26 eyes) scheduled for small-incision extracapsular cataract extraction by phacoemulsification with implantation of the Synchrony dual-optic accommodating IOL (Visiogen) (accommodating IOL group) and 10 patients who had small-incision extracapsular phacoemulsification with implantation of a monofocal, single-optic IOL at least 6 months previously (control group).With distance correction, 23 eyes (96%) had an acuity of 20/40 or better at near.Defocus curve analysis suggested a mean accommodative range of 3.22 diopters (D) ± 0.88 (SD) (range 1.00 to 5.00 D) in the accommodating IOL group and 1.65 ± 0.58 D in the control group (range 1.00 to 2.50 D) (Supported in part by unrestricted grants from That Man May See, San Francisco, California, and Research to Prevent Blindness, New York, New York, USA. Ossma, Galvis, Vagefi, and Trager have no financial or proprietary interest in any material or method mentioned. Vargas and Mc Leod have a financial interest in Visiogen Inc., and in the intraocular lens described.

Method: Ray tracing analysis and lens design; cadaver eye implantation.The anterior translation member and the posterior translation member connected at an apex.The anterior translation member capable of moving an optic of the anterior viewing element relative to an optic of the posterior viewing along an optical axis of the lens such that the anterior optic and the posterior optic are positioned further apart when the anterior optic is in the accommodated position than when the anterior optic is in the unaccommodated position. An accommodating intraocular lens for implantation in an eye having an optical axis, said lens comprising:an anterior viewing element comprised of an optic having refractive power;a first anterior translation member connected to said anterior viewing element at first and second attachment locations;a posterior viewing element comprised of an optic having refractive power;a first posterior translation member connected to said posterior viewing element at third and fourth attachment locations, said first anterior translation member and said first posterior translation member connected at a first apex such that all of said first, second, third and fourth attachment locations are interconnected to one another through said anterior translation member and said posterior translation member;said anterior viewing element optic being mounted to move relative to said posterior viewing element optic along the optical axis between an accommodated position and an unaccommodated position in response to action of the ciliary muscle of the eye, said relative movement corresponding to change in the combined refractive power of the optics of at least one diopter;wherein said lens is configured such that, when said lens is implanted in the eye, said posterior viewing element optic is substantially stationary with respect to a location on said optical axis during movement of said anterior viewing element optic;wherein said anterior viewing element optic and said posterior viewing element optic are positioned further apart when said anterior viewing element optic is in the accommodated position than when said anterior viewing element optic is in the unaccommodated position, and said anterior viewing element optic is biased toward said accommodated position. The lens of Claim 1, wherein said optics are mounted to move relative to each other along the optical axis in response to a contractile force by the ciliary muscle of the eye upon the capsular bag of the eye of up to 2.0 grams. The lens of Claim 1 or 2, wherein:at least one of said viewing element optics is a biconvex optic; said biconvex optic has first and second surfaces; said first surface has a radius of curvature of about 5.944 mm; and said second surface has a radius of curvature of about 5.944 mm. The lens of Claim 1 or 2, wherein:at least one of said viewing element optics is a biconvex optic; said biconvex optic has first and second surfaces; said first surface has a radius of curvature of about 5.656 mm; and said second surface has a radius of curvature of about 7.788 mm. The lens of Claim 1 or 2, wherein:at least one of said viewing element optics is a biconvex optic; said biconvex optic has first and second surfaces; said first surface has a radius of curvature of about 6.961 mm; and said second surface has a radius of curvature of about 8.5 mm. The lens of Claim 1 or 2, wherein:at least one of said viewing element optics is a biconcave optic; said biconcave optic has first and second surfaces; said first surface has a radius of curvature of about 18.765 mm; and said second surface has a radius of curvature of about 18.765 mm. The lens of Claim 1 or 2, wherein:at least one of said viewing element optics is a concave-convex optic;said concave-convex optic has anterior and posterior surfaces;said concave-convex optic has a refractive power of -8 diopter;said anterior surface has a radius of curvature of about 9 mm to about 9.534 mm; and said posterior surface has a radius of curvature of about 40 mm. The lens of Claim 1 or 2, wherein:at least one of said viewing element optics is a concave-convex optic;said concave-convex optic has anterior and posterior surfaces;said concave-convex optic has a refractive power of -5 diopter;said anterior surface has a radius of curvature of about 9 mm to about 9.534 mm; and said posterior surface has a radius of curvature of about 20 mm. The lens of any one of Claims 1 to 20, wherein said relative movement of said optics includes an accommodated position and an unaccommodated position, said optics being about 0.5 to about 4 millimeters closer together when in the unaccommodated position. The lens of any one of Claims 1 to 20, wherein said relative movement of said optics includes an accommodated position and an unaccommodated position, said optics being about 1 to about 3 millimeters closer together when in the unaccommodated position, 23.SAN FRANCISCO -- A novel, "dual optic" accommodating intraocular lens improved intermediate distance vision and contrast sensitivity under low light conditions compared with some multifocal lenses, researchers said.The findings, reported in two studies from the same research group here at the American Academy of Ophthalmology meeting, suggest that the new generation of lens will hold functional advantages for patients undergoing cataract surgery."In the past, we only looked at visual acuity," said presenter Andrea Galvis, MD, of the Fundación Valle del Lili in Cali, Colombia.