Sagal portrayed his wife, the family's voice of reason, Cuoco his eldest daughter, the stock ditzy blonde.
Ritter, an icon in the world of American television for his star turn on Three's Company, died in 2003 from a misdiagnosed thoracic aortic aneurysm.
A nationally syndicated columnist with the Rocky Mountain News, Cameron gained national attention with the publication of 8 SIMPLE RULES in hardcover, becoming a regular contributor to Time's "Your Family" column and a featured story on CNN, CBS's The Early Show, and in People magazine.
You learn what to do on a date following step by step instructions.
On Thursday, she uploaded an Instagram photo of herself reuniting with the original cast of the ABC programme 8 Simple Rules For Dating My Teenage Daughter - except, of course, for the late John Ritter.
Her black-and-white snapshot showed the 30-year-old leaning into frame and grinning broadly alongside Katey Sagal, who played her mother, as well as Martin Spanjers and Amy Davdison, who played her younger siblings.
The 54-year-old had been rushed to hospital straight from a rehearsal for 8 Simple Rules For Dating My Teenage Daughter.
The final series, its title trimmed down to 8 Simple Rules, ended in 2005, having won a cinematography Emmy in 2004.